BDBM715376 (1,4-diazabicyclo[3.2.2] nonan-4-yl)(3-(3,4,5- trifluorophenyl)-6,7- dihydropyrano[4,3-c] pyrazol-1(4H)-yl)meth- anone::US20250026762, Compound 46

SMILES O=C(N1CCN2CCC1CC2)n1nc(-c2cc(F)c(F)c(F)c2)c2c1CCOC2

InChI Key InChIKey=CIEAMRWRUPMDHW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715376   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM715376((1,4-diazabicyclo[3.2.2] nonan-4-yl)(3-(3,4,5- tri...)
Affinity DataEC50:  4.60nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent