BDBM715619 US20250026766, Example 104

SMILES COc1cccc(F)c1-c1cc(C)ncc1C(=O)Nc1nc2ccc(-c3ccc(C#N)cc3)nc2s1

InChI Key InChIKey=FTQFXQBEJLJGJQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715619   

TargetDNA polymerase theta [1-894](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM715619(US20250026766, Example 104)
Affinity DataIC50: 6.5nMAssay Description:Enzymatic reactions of Pol Theta (1-894) were performed using ADP-Glo assay with ssDNA substrate. Pol Theta (1-894) was expressed in baculovirus expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2025
Entry Details
US Patent