BDBM716465 US20250034112, Compound 33j

SMILES N#Cc1ccc(Nc2nc(N)nc(Oc3ccc4[nH]c(COCC(=O)O)cc4c3)n2)cc1

InChI Key InChIKey=VWFSPMHJQFYJIC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 716465   

TargetTyrosine-protein kinase JAK2 [536-812,V617F](Human)
Yale University

US Patent
LigandPNGBDBM716465(US20250034112, Compound 33j)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Yale University

US Patent
LigandPNGBDBM716465(US20250034112, Compound 33j)
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent