BDBM716831 US20250034135, Compound a

SMILES COc9ccc(CN8CCN(C6CC5(CCN(c4ccc(C(=O)NS(=O)(=O)c2ccc(NC[C@@H]1CC[C@@](C)(O)CC1)c([N+](=O)[O-])c2)c(OC(C=N)Cc3cc[nH]c3)c4)CC5)C6)[C@H](c7ccccc7C(C)C)C8)cc9

InChI Key InChIKey=SKTVZFQJPWNJPO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 716831   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716831(US20250034135, Compound a)
Affinity DataIC50: 233nMAssay Description:In a white shallow 384-well plate, a total reaction volume was 10 μL. Specifically, it included 2 μL of the compound to be tested (2% DMSO), 4 L His-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716831(US20250034135, Compound a)
Affinity DataIC50: 2.55E+3nMAssay Description:The inhibitory activity of compounds on human CYP3A4 enzyme was detected using a VIVID™ CYP3A4 GREEN SCRNING KIT reagent kit. The Vivid™ CYP450 scree...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent