BDBM716837 N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(6-ethyl-7-(4-(4-hydroxy-2- methoxynicotinoyl)piperazin-1-yl)-3-methyl-8-oxopyrido[2,3- b]pyrazin-5(8H)-yl)acetamide::US20250034136, Compound I-6
SMILES CCc1c(N2CCN(C(=O)c3c(O)ccnc3OC)CC2)c(=O)c2ncc(C)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl
InChI Key InChIKey=MXBGBYMPONBTQG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 716837
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1235,L1074F](Human)
Nimbus Wadjet
US Patent
Nimbus Wadjet
US Patent
Affinity DataIC50: 27.5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
