BDBM719123 US20250049780, Example 49

SMILES Cc1c([C@@H]2C[C@H]3CC[C@@H](C2)N3CC(N)=O)sc2[nH]c(-c3cn4ncnc4c4c3COC4)c(C(C)C)c12

InChI Key InChIKey=OCZIELYOWCTTPL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719123   

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719123(US20250049780, Example 49)
Affinity DataEC50:  0.410nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719123(US20250049780, Example 49)
Affinity DataEC50:  15.2nMAssay Description:Cryopreserved human PBMCs from healthy donors were thawed and resuspended in RPMI-1640 media with L-glutamine (Corning) supplemented with 10% Fetal B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent