BDBM719600 3-chloro-4-((1S,2S)-2-(5-chloropyridin-3-yl)cyclopropyl)-2''-(2-fluoro-3-(3-::US20250051309, Example 6.41

SMILES Cc1nscc1-c1cccc(-c2cc(-n3c(C)cc([C@H]4C[C@@H]4c4cncc(Cl)c4)c(Cl)c3=O)c(C)cn2)c1F

InChI Key InChIKey=CYJWXNOPHVYBKD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719600   

TargetMitogen-activated protein kinase 14/1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719600(3-chloro-4-((1S,2S)-2-(5-chloropyridin-3-yl)cyclop...)
Affinity DataIC50: 0.700nMAssay Description:In a 20 μL reaction, the compounds of various concentrations (20 nL) were pre-incubated with 0.6 nM MK2 (Abcam #ab79910) and 0.06 nM active p38α (Abc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

LigandPNGBDBM719600(3-chloro-4-((1S,2S)-2-(5-chloropyridin-3-yl)cyclop...)
Affinity DataIC50: 68.1nMAssay Description:In a 10 μL reaction, the compounds of various concentrations (10 nL) were pre-incubated with 3 nM active p38 at (Abcam #ab271606 or in-house prepared...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent