BDBM719606 3-chloro-3''-fluoro-2''-(2-fluoro-3-(3-methyl-4H-1,2,4-triazol-4-yl)phenyl)-4-::US20250051309, Example 6.47

SMILES Cc1cnc(-c2cccc(-n3cnnc3C)c2F)c(F)c1-n1c(C)cc([C@H]2C[C@@H]2c2cncc(F)c2)c(Cl)c1=O

InChI Key InChIKey=IYPVCRHLVNPFHJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719606   

TargetMitogen-activated protein kinase 14/1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719606(3-chloro-3'-fluoro-2'-(2-fluoro-3-(3-methyl-4H-1,2...)
Affinity DataIC50: 0.200nMAssay Description:In a 20 μL reaction, the compounds of various concentrations (20 nL) were pre-incubated with 0.6 nM MK2 (Abcam #ab79910) and 0.06 nM active p38α (Abc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

LigandPNGBDBM719606(3-chloro-3'-fluoro-2'-(2-fluoro-3-(3-methyl-4H-1,2...)
Affinity DataIC50: 8.5nMAssay Description:In a 10 μL reaction, the compounds of various concentrations (10 nL) were pre-incubated with 3 nM active p38 at (Abcam #ab271606 or in-house prepared...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent