BDBM719623 3-chloro-3''-fluoro-2''-(2-fluoro-3-(4-methyl-1H-imidazol-1-yl)phenyl)-4-((1S,2S)-2-::US20250051309, Example 6.64

SMILES Cc1cn(-c2nccc(-c3ncc(C)c(-n4c(C)cc([C@H]5C[C@@H]5c5cncc(F)c5)c(Cl)c4=O)c3F)c2F)cn1

InChI Key InChIKey=XKWJHHAYVXZFEF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719623   

TargetMitogen-activated protein kinase 14/1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719623(3-chloro-3'-fluoro-2'-(2-fluoro-3-(4-methyl-1H-imi...)
Affinity DataIC50: 0.400nMAssay Description:In a 20 μL reaction, the compounds of various concentrations (20 nL) were pre-incubated with 0.6 nM MK2 (Abcam #ab79910) and 0.06 nM active p38α (Abc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

LigandPNGBDBM719623(3-chloro-3'-fluoro-2'-(2-fluoro-3-(4-methyl-1H-imi...)
Affinity DataIC50: 9.20nMAssay Description:In a 10 μL reaction, the compounds of various concentrations (10 nL) were pre-incubated with 3 nM active p38 at (Abcam #ab271606 or in-house prepared...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent