BDBM719833 N-((5-(2-((2-ethyl-6- (trifluoromethyl)-2H-pyrazolo[3,4- d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)-2-hydroxyacetamide::US20250051319, Compound 135::US12421222, Compound 135
SMILES CCn1cc2c(SCC(=O)c3ccc(CNC(=O)CO)s3)nc(C(F)(F)F)nc2n1
InChI Key InChIKey=PEXQVLSQGHIUTB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 719833
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-terminal G...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair