BDBM719834 N-((5-(2-((1-ethyl-6- (trifluoromethyl)-1H-pyrazolo[3,4- d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)-2-hydroxyacetamide::US20250051319, Compound 136

SMILES CCn1ncc2c(SCC(=O)c3ccc(CNC(=O)CO)s3)nc(C(F)(F)F)nc21

InChI Key InChIKey=AWSRLAPYZJXLPK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719834   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719834(N-((5-(2-((1-ethyl-6- (trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent