BDBM719843 N-((5-(2-((6-ethoxy-2- methylpyrido[3,4-d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)-2-hydroxyacetamide::US20250051319, Compound 145

SMILES CCOc1cc2c(SCC(=O)c3ccc(CNC(=O)CO)s3)nc(C)nc2cn1

InChI Key InChIKey=RPTJYBHANGULTA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719843   

TargetHistone deacetylase 6 [482-800](Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719843(N-((5-(2-((6-ethoxy-2- methylpyrido[3,4-d]pyrimidi...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent