BDBM719845 N-((5-(2-((6-(2-oxa-5- azabicyclo[2.2.2]octan-5-yl)-2- methylquinazolin-4- yl)thio)acetyl)thiophen-2- yl)methyl)-2-hydroxyacetamide::US20250051319, Compound 147::US12421222, Compound 147

SMILES Cc1nc(SCC(=O)c2ccc(CNC(=O)CO)s2)c2cc(N3CC4CCC3CO4)ccc2n1

InChI Key InChIKey=SOMAXXKPNHQKLF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 719845   

TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM719845(N-((5-(2-((6-(2-oxa-5- azabicyclo[2.2.2]octan-5-yl...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM719845(N-((5-(2-((6-(2-oxa-5- azabicyclo[2.2.2]octan-5-yl...)
Affinity DataIC50: 100nMAssay Description:Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-terminal G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM719845(N-((5-(2-((6-(2-oxa-5- azabicyclo[2.2.2]octan-5-yl...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent