BDBM71991 6-amino-1'-benzyl-2'-keto-3-propyl-spiro[2H-pyrano[2,3-c]pyrazole-4,3'-indoline]-5-carboxylic acid methyl ester::6-amino-2'-oxo-1'-(phenylmethyl)-3-propyl-5-spiro[2H-pyrano[2,3-c]pyrazole-4,3'-indole]carboxylic acid methyl ester::MLS000558098::SMR000148814::cid_3981800::methyl 6-amino-1'-benzyl-2'-oxo-3-propylspiro[2H-pyrano[2,3-c]pyrazole-4,3'-indole]-5-carboxylate::methyl 6-azanyl-2'-oxidanylidene-1'-(phenylmethyl)-3-propyl-spiro[2H-pyrano[2,3-c]pyrazole-4,3'-indole]-5-carboxylate

SMILES CCCc1[nH]nc2OC(=N)C(C(=O)OC)C3(C(=O)N(Cc4ccccc4)c4ccccc34)c12

InChI Key InChIKey=LTCCOPMKGOMORD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 71991   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 71991BDBM71991(4-[5-[3-(m-tolyl)pyrazol-1-yl]-2- thiazol-2-yl-pyr...)
Affinity DataIC50: 2.70nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details PCBioAssay