BDBM719985 US20250051321, Compound GLPG1690::WO2014139882, Compound 2

SMILES CCc1nc2c(C)cc(N3CCN(CC(=O)N4CC(O)C4)CC3)cn2c1N(C)c1nc(-c2ccc(F)cc2)c(C#N)s1

InChI Key InChIKey=REQQVBGILUTQNN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 719985   

TargetAutotaxin(Human)TBA
LigandPNGBDBM719985(US20250051321, Compound GLPG1690 | WO2014139882, C...)
Affinity DataIC50: 5nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetPeroxidase C1A/Choline Oxidase(Horseradish)
Shanghai Jemincare Pharmaceutical

US Patent
LigandPNGBDBM719985(US20250051321, Compound GLPG1690 | WO2014139882, C...)
Affinity DataIC50: 305nMAssay Description:All compounds were prepared as a 10 mM DMSO stock solution. The positive control compound GLPG1690 was prepared as a 10 mM DMSO stock solution.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetPeroxidase C1A/Choline Oxidase(Horseradish)
Shanghai Jemincare Pharmaceutical

US Patent
LigandPNGBDBM719985(US20250051321, Compound GLPG1690 | WO2014139882, C...)
Affinity DataIC50: 1.75E+3nMAssay Description:All compounds were prepared as a 10 mM DMSO stock solution. The positive control compound GLPG1690 was prepared as a 10 mM DMSO stock solution.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent