BDBM720224 preparation of (R)—N-methyl-5-(2-methyl-4-((4-methyl-2-oxo-3-(trifluoromethyl)-1,2-dihydro-1,6-naphthyridin-7-yl)methyl)piperazin-1-yl)picolinamide (::US20250051324, Example 88

SMILES CNC(=O)c1ccc(N2CCN(Cc3cc4c(cn3)C(C)=C(C(F)(F)F)C(=O)C4)C[C@H]2C)cn1

InChI Key InChIKey=SOOIWXOVXKQWIQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720224   

TargetPoly [ADP-ribose] polymerase 1(Human)
Keythera (Suzhou) Bio-Pharmaceuticals

US Patent
LigandPNGBDBM720224(preparation of (R)—N-methyl-5-(2-methyl-4-((4-meth...)
Affinity DataIC50: 1.55nMAssay Description:The PARP1 assay kit was purchased from BPS Bioscience, USA, specifically the 384-well chemiluminescent assay kit (Catalog No.: #80551).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent