BDBM72027 (E)-1-[1-[2-(4-methoxyphenyl)-2-oxidanylidene-ethyl]benzimidazol-2-yl]-3-phenyl-prop-2-en-1-one::(E)-1-[1-[2-(4-methoxyphenyl)-2-oxoethyl]-2-benzimidazolyl]-3-phenyl-2-propen-1-one::(E)-1-[1-[2-(4-methoxyphenyl)-2-oxoethyl]benzimidazol-2-yl]-3-phenylprop-2-en-1-one::(E)-1-[1-[2-keto-2-(4-methoxyphenyl)ethyl]benzimidazol-2-yl]-3-phenyl-prop-2-en-1-one::1-{1-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-benzimidazol-2-yl}-3-phenyl-2-propen-1-one::MLS000324911::SMR000163975::cid_5832237

SMILES Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@@](C)(C[C@@H](C)N(C)C)C5)cn4)ncc3F)cc2n1C(C)C

InChI Key InChIKey=AVRWJSHUUIQGJM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72027   

TargetCyclin-dependent kinase 6(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72027BDBM72027(US12486280, Compound A28)
Affinity DataKi:  460nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72027BDBM72027(US12486280, Compound A28)
Affinity DataKi:  2.60E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 4(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72027BDBM72027(US12486280, Compound A28)
Affinity DataIC50: 6.78E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent