BDBM720589 (R)-3-methyl-4-(1-(methylsulfonyl)-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-morpholine ::US20250051362, Compound 12::US12435095, Compound 12

SMILES C[C@@H]1COCCN1c1cc(-c2ncnc3[nH]ccc23)nc2c1ccn2S(C)(=O)=O

InChI Key InChIKey=LCMFZJSNGJKFQX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 720589   

TargetSerine/threonine-protein kinase ATR(Human)
Shanghai Annova Biotechnology

US Patent
LigandPNGBDBM720589((R)-3-methyl-4-(1-(methylsulfonyl)-6-(7H-pyrrolo[2...)
Affinity DataIC50: 130nMAssay Description:The inhibitory activity of the compounds on ATR kinase in vitro was determined by Mobility Shift Assay at an ATP concentration of Km using Caliper EZ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Shanghai Annova Biotechnology

US Patent
LigandPNGBDBM720589((R)-3-methyl-4-(1-(methylsulfonyl)-6-(7H-pyrrolo[2...)
Affinity DataIC50: 130nMAssay Description:Experimental method: The inhibitory activity of the compounds on ATR kinase in vitro was determined by Mobility Shift Assay at an ATP concentration o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent