BDBM720786 Synthesis of ((R)-3-methyl-1-((R)-3-(1-methyl-1H-Imidazol-2-yl)-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid (Compound 8) and ((R)-3-methyl-1-((S)-3-(1-methyl-1H-imidazol-2-yl)-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid ::US20250051367, Compound 9

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1nccn1C)NC(=O)c1cnccn1)B(O)O

InChI Key InChIKey=VRMHUSYXNDNDGM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720786   

TargetLon protease homolog, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM720786(Synthesis of ((R)-3-methyl-1-((R)-3-(1-methyl-1H-I...)
Affinity DataIC50: 275nMAssay Description:In this Example, LONP1 (NM_004793.4) activity was measured by a FRET-based assay for protease activity using a fluorogenic peptide DabcylYRGIT(2Abu)S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
6/17/2025
Entry Details
US Patent