BDBM720832 US20250051375, Compound 42

SMILES C=C(C[C@@H](CN(Cc1c(F)cc(-c2ccn(C(F)F)n2)cc1F)NC(=O)[C@@H](CC(=O)OC)C(C)(C)C(F)(F)F)[C@@H](CC(=O)[C@@H](NC(=O)OC)C(C)(C)C(F)(F)F)Cc1ccc(C#Cc2cnc(N3CC4CCC(C3)N4C3COC3)nc2)cc1)CC(C)(C)c1c(CC(=O)NC(CCC(=O)O)CCC(=O)O)cc(C)cc1OP(=O)(O)O

InChI Key InChIKey=MROVUAQNGISJNR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720832   

TargetHIV-1 protease(Human immunodeficiency virus)
Gilead Sciences

US Patent
LigandPNGBDBM720832(US20250051375, Compound 42)
Affinity DataEC50:  49.1nMAssay Description:Test compounds and controls were serially diluted and spotted in replicate into 384 well black assay plates via acoustic transfer (Echo). MT-4 cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent