BDBM721039 8-(6-(3-(dimethylamino)propoxy)pyridin-3-yl)-7-fluoro-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]cinnolin-2(3H)-one::US12226414, Example 19

SMILES CN(C)CCCOc1ccc(-c2cc3c(cc2F)nnc2c3n(C3CCOCC3)c(=O)n2C)cn1

InChI Key InChIKey=VBBRGFYIHDIPIX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721039   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM721039(8-(6-(3-(dimethylamino)propoxy)pyridin-3-yl)-7-flu...)
Affinity DataIC50: 13nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1× kinase base buffer. 10 μl of 2× enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent