BDBM72112 4-chloranyl-N-[2-(1,3-dimethyl-5-phenoxy-pyrazol-4-yl)ethyl]benzenesulfonamide::4-chloro-N-[2-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)ethyl]benzenesulfonamide::4-chloro-N-[2-(1,3-dimethyl-5-phenoxy-4-pyrazolyl)ethyl]benzenesulfonamide::4-chloro-N-[2-(1,3-dimethyl-5-phenoxy-pyrazol-4-yl)ethyl]benzenesulfonamide::4-chloro-N-[2-(1,3-dimethyl-5-phenoxypyrazol-4-yl)ethyl]benzenesulfonamide::MLS000331228::SMR000168692::cid_4421379

SMILES Cc1nn(C)c(Oc2ccccc2)c1CCNS(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=JDGGTYAATFHXKW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72112   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 72112BDBM72112(N-(2-(1-cyclopropyl-1H-pyrazol-4-yl)pyrimidin-4-yl...)
Affinity DataIC50: 1.90nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details PCBioAssay
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 72112BDBM72112(N-(2-(1-cyclopropyl-1H-pyrazol-4-yl)pyrimidin-4-yl...)
Affinity DataIC50: 2.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details PCBioAssay