BDBM72124 (2,2,4-trimethyl-1H-quinolin-6-yl) 2-(1,3-dioxoisoindol-2-yl)-3-phenylpropanoate::(2,2,4-trimethyl-1H-quinolin-6-yl) 2-[1,3-bis(oxidanylidene)isoindol-2-yl]-3-phenyl-propanoate::2,2,4-trimethyl-1,2-dihydro-6-quinolinyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoate::2-(1,3-dioxo-2-isoindolyl)-3-phenylpropanoic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester::3-phenyl-2-phthalimido-propionic acid (2,2,4-trimethyl-1H-quinolin-6-yl) ester::MLS000570611::SMR000187235::cid_2869917

SMILES CC1=CC(C)(C)Nc2ccc(OC(=O)C(Cc3ccccc3)N3C(=O)c4ccccc4C3=O)cc12

InChI Key InChIKey=IIHUBEYEWFIAGO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72124   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 72124BDBM72124(N-(2-(1-(cyclopropylsulfonyl)-1H-pyrazol-4-yl)pyri...)
Affinity DataIC50: 9.40nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details PCBioAssay