BDBM721241 2-isopropyl-8-(6-methyl- 7-oxo-6,7-dihydro-1H- pyrrolo[2,3-c]pyridin-4- yl)-6-(morpholin-4- ylcarbonyl)-2H-1,4- benzoxazin-3(4H)-one::US12227502, Example 33

SMILES CC(C)C1Oc2c(cc(C(=O)N3CCOCC3)cc2C2CN(C)C(=O)c3[nH]ccc32)NC1=O

InChI Key InChIKey=MKCVORUHQXNTSA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 721241   

TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent
LigandPNGBDBM721241(2-isopropyl-8-(6-methyl- 7-oxo-6,7-dihydro-1H- pyr...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent
LigandPNGBDBM721241(2-isopropyl-8-(6-methyl- 7-oxo-6,7-dihydro-1H- pyr...)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent