BDBM72127 (E)-3-(3-bromanyl-4-methoxy-phenyl)-N,N-di(propan-2-yl)prop-2-enamide::(E)-3-(3-bromo-4-methoxy-phenyl)-N,N-diisopropyl-acrylamide::(E)-3-(3-bromo-4-methoxyphenyl)-N,N-di(propan-2-yl)-2-propenamide::(E)-3-(3-bromo-4-methoxyphenyl)-N,N-di(propan-2-yl)prop-2-enamide::3-(3-bromo-4-methoxyphenyl)-N,N-diisopropylacrylamide::MLS000571322::SMR000193691::cid_718487

SMILES COc1ccc(\C=C\C(=O)N(C(C)C)C(C)C)cc1Br

InChI Key InChIKey=APDMHZKESGQPPV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72127   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Shanghai Hansoh Biomedical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 72127BDBM72127(2-(4-(4-((5-isopropyl-8-((2R,3S)-2-methyl-3-((meth...)
Affinity DataIC50: 4.20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details PCBioAssay