BDBM721395 US12227517, Example 12

SMILES O=C(Nc1ccc(Oc2ccccc2)c(C(F)(F)F)c1N1CCOC2(CCNCC2)C1)c1csc(-c2ccnnc2)n1

InChI Key InChIKey=CGBGZQWCYALWES-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721395   

TargetDiacylglycerol kinase epsilon(Human)
Astellas Pharma

US Patent
LigandPNGBDBM721395(US12227517, Example 12)
Affinity DataIC50: 17nMAssay Description:To a 384-well plate (Greiner Bio-One Co., Ltd.), 3 μL of a DGK Δ enzyme dissolved in an assay buffer (40 mM Tris-HCl pH 7.5, 10 mM MgCl2, 1 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent