BDBM721549 methyl (E)-4-(2-((S)-3-amino-2-((1-((R)-1-(naphthalen-1-yl)ethyl)piperidin-4-yl)amino)propanamido)acetamido)but-2-enoate::US20250059159, Compound 26

SMILES COC(=O)/C=C/CNC(=O)CNC(=O)[C@H](CN)NC1CCN([C@H](C)c2cccc3ccccc23)CC1

InChI Key InChIKey=JEWMDCRMVILSIK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721549   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Synergy Pharmaceutical Sciences

US Patent
LigandPNGBDBM721549(methyl (E)-4-(2-((S)-3-amino-2-((1-((R)-1-(naphtha...)
Affinity DataIC50: 550nMAssay Description:The PLpro enzyme was purified as described above and prepared in assay buffer (50 mM HEPES, pH 7.5, 0.01% Triton X-100 (v/v), 0.1 mg mL-1 BSA, and 2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent