BDBM722453 US20250059185, Example 55

SMILES CC1C2=NN(C)C(C3=CC(C4(NS(C)(=O)=O)CC4)=CC(Cl)C3)C2CCN1C(=O)c1cc(F)cc(-c2ccc(=O)[nH]c2)c1Cl

InChI Key InChIKey=MDBKZXJZFRFZRZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722453   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM722453(US20250059185, Example 55)
Affinity DataIC50: 7nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent