BDBM722610 N-(4-(4-amino-7-(1-(1- (isopropyl(methyl)amino)propan- 2-yl)-1H-pyrazol-4-yl)-1- methyl-1H-pyrazolo[4,3- c]pyridin-3-yl)-2-((S)-1-(4- fluorophenyl)ethoxy)phenyl)-1,1- difluoromethanesulfonamide::US20250059188, Compound 101::US20250115598, Compound 101
SMILES CC(C)N(C)CC(C)n1cc(-c2cnc(N)c3c(-c4ccc(NS(=O)(=O)C(F)F)c(O[C@@H](C)c5ccc(F)cc5)c4)nn(C)c23)cn1
InChI Key InChIKey=WCFAEIYJRUNDEI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 722610
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair