BDBM722650 N-(4-(4-amino-1- methyl-7-(1- (tetrahydro-2H-pyran- 4-yl)-1H-pyrazol-4-yl)- 1H-pyrazolo[4,3- c]pyridin-3-yl)-2- (thiazol-2- ylmethoxy)phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 143::US20250115598, Compound 143
SMILES Cn1nc(-c2ccc(NS(=O)(=O)C(F)F)c(OCc3nccs3)c2)c2c(N)ncc(-c3cnn(C4CCOCC4)c3)c21
InChI Key InChIKey=NMXXFYBLBNSTNN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 722650
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair