BDBM72266 (3Z)-1-methyl-5-(morpholin-4-ylsulfonyl)-1H-indole-2,3-dione 3-[N-(4-methylphenyl)thiosemicarbazone]::1-[(Z)-(1-methyl-5-morpholin-4-ylsulfonyl-2-oxidanylidene-indol-3-ylidene)amino]-3-(4-methylphenyl)thiourea::1-[(Z)-(1-methyl-5-morpholin-4-ylsulfonyl-2-oxoindol-3-ylidene)amino]-3-(4-methylphenyl)thiourea::1-[(Z)-(2-keto-1-methyl-5-morpholinosulfonyl-indolin-3-ylidene)amino]-3-(p-tolyl)thiourea::1-[(Z)-[1-methyl-5-(4-morpholinylsulfonyl)-2-oxo-3-indolylidene]amino]-3-(4-methylphenyl)thiourea::MLS000586623::SMR000208002::cid_6018710

SMILES O=C1CCC(N2Cc3cc(N4CCC(CN5CCCN(c6cccc(-c7cnc8[nH]cc(CC(F)F)c8c7Cl)c6)C5=O)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=HSRNSAWDFABMJB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72266   

LigandChemical structure of BindingDB Monomer ID 72266BDBM72266(3-(5-{4-[(3-{3-[4-chloro-3-(2, 2-difluoroethyl)-1H...)
Affinity DataIC50: 25.8nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent