BDBM72268 3-phenyl-5-(2-phenylvinyl)-2-cyclohexen-1-one::3-phenyl-5-[(E)-2-phenylethenyl]-1-cyclohex-2-enone::3-phenyl-5-[(E)-2-phenylethenyl]cyclohex-2-en-1-one::3-phenyl-5-[(E)-styryl]cyclohex-2-en-1-one::MLS000700798::SMR000229738::cid_11841586

SMILES CCc1c[nH]c2ncc(-c3cccc(N4CCCN(CC5CCN(c6ccc(NC7CCC(=O)NC7=O)cc6F)CC5)C4=O)c3)c(Cl)c12

InChI Key InChIKey=NIARZVSDSHNPGJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72268   

LigandChemical structure of BindingDB Monomer ID 72268BDBM72268(3-((4-(4-((3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2, 3...)
Affinity DataIC50: 4.60nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 72268BDBM72268(3-((4-(4-((3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2, 3...)
Affinity DataIC50: 8.80nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

TargetAurora kinase A(Human)
Biofront

US Patent
LigandChemical structure of BindingDB Monomer ID 72268BDBM72268(3-((4-(4-((3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2, 3...)
Affinity DataIC50: 19.9nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent