BDBM722695 1(2-carbonyl-1,2-dihydropyrrolo[4,3,2-ij]isoquinolin-6-yl)-5-trifluoromethyl-N-(2-trifluoromethyl pyridin-4-yl)-1H-pyrazole-4-carboxamide::US20250059196, Example 3

SMILES O=C(Nc1ccnc(C(F)(F)F)c1)c1cnn(-c2ccc3c4c(cccc24)C(=O)N3)c1C(F)(F)F

InChI Key InChIKey=HXGHKYGEUCRBQN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722695   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM722695(1(2-carbonyl-1,2-dihydropyrrolo[4,3,2-ij]isoquinol...)
Affinity DataIC50: 105nMAssay Description:1.1 Experimental PurposeAc-LRSR-AMC was used as the substrate to test the IC50 of the inhibitory activity of compounds on MALT1 enzyme activity at th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent