BDBM72304 5,6-dimethyl-2-[[3-(trifluoromethyl)phenyl]sulfanylmethyl]-3H-thieno[2,3-d]pyrimidin-4-one::5,6-dimethyl-2-[[[3-(trifluoromethyl)phenyl]thio]methyl]-3H-thieno[2,3-d]pyrimidin-4-one::MLS000393396::SMR000243829::cid_2077883

SMILES O=C1c2cc(C(F)(F)F)ccc2N2CN1c1cc[n+]([O-])cc1CCCCCc1cc(F)ccc12

InChI Key InChIKey=QLDFOIBUXWJYGE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72304   

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandChemical structure of BindingDB Monomer ID 72304BDBM72304(34-Fluoro-24-oxo-26-(trifluoromethyl)-21,22,23,24-...)
Affinity DataIC50: 5.01nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2026
Entry Details
US Patent