BDBM723354 US20250059185, Example 38

SMILES C[C@@H]3c2nn(C)c(c1cc(F)cc(F)c1)c2CCN3C(=O)c5cc(F)cc(OC[C@H]4CNC(=O)C4)c5Cl

InChI Key InChIKey=UJYBVEAPROIDDA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 723354   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM723354(US20250059185, Example 38)
Affinity DataIC50: 0.5nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent