BDBM724054 US20250066290, Example 5/1

SMILES [2H]c1c([2H])c([2H])c(-c2c(F)c(F)c(NC(=O)C3=C(C(=O)NOC([2H])([2H])[2H])COC3)c(F)c2F)c([2H])c1[2H]

InChI Key InChIKey=ZHXNOEXDZRRVIZ-JGUCLWPXSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724054   

LigandPNGBDBM724054(US20250066290, Example 5/1)
Affinity DataIC50: 100nMAssay Description:The in vitro inhibition of hDHODH was measured using an N-terminally truncated recombinant hDHODH enzyme as described in J. Med. Chem. 2006; 49:1239....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent