BDBM724099 US20250066290, Example 17-2

SMILES [2H]C([2H])([2H])Oc1cccc(-c2c(F)c(F)c(NC(=O)c3sc(C)cc3C(=O)NOC)c(F)c2F)c1

InChI Key InChIKey=ZJIGNCFSKMXNJV-BMSJAHLVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724099   

LigandPNGBDBM724099(US20250066290, Example 17-2)
Affinity DataIC50: 100nMAssay Description:The in vitro inhibition of hDHODH was measured using an N-terminally truncated recombinant hDHODH enzyme as described in J. Med. Chem. 2006; 49:1239....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent