BDBM72432 (4E)-5-methyl-2-phenyl-4-[(2-phenylethylamino)methylidene]-3-pyrazolone::(4E)-5-methyl-2-phenyl-4-[(2-phenylethylamino)methylidene]pyrazol-3-one::(4E)-5-methyl-4-[(phenethylamino)methylene]-2-phenyl-2-pyrazolin-3-one::5-methyl-2-phenyl-4-{[(2-phenylethyl)amino]methylene}-2,4-dihydro-3H-pyrazol-3-one::MLS000626708::SMR000299094::cid_6373166

SMILES Cc5cccc(c2nc1NCCn1c2c4ccc(F)c(NC(=O)CCN3CCN(CC(F)(F)F)CC3)c4)n5

InChI Key InChIKey=UUSHVHZSHPDPSW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72432   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 72432BDBM72432(N-(2-fluoro-5-(6-(6-methylpyridin-2- yl)-2,3-dihyd...)
Affinity DataIC50: 4.60nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent