BDBM72436 (E)-1-(1-adamantyl)-3-[4-methoxy-3-(4-morpholinylmethyl)phenyl]-2-propen-1-one::(E)-1-(1-adamantyl)-3-[4-methoxy-3-(morpholin-4-ylmethyl)phenyl]prop-2-en-1-one::(E)-1-(1-adamantyl)-3-[4-methoxy-3-(morpholinomethyl)phenyl]prop-2-en-1-one::MLS000680270::SMR000268418::cid_5729167

SMILES CN1CCN(CCC(=O)Nc2cc(-c3c(-c4cc(Cl)ccc4F)nc4n3CCN4)ccc2F)CC1

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72436   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 72436BDBM72436(N-(5-(6-(5-chloro-2-fluorophenyl)-2,3- dihydro-1H-...)
Affinity DataIC50: 4.60nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent