BDBM72437 1-(2,5-dichlorophenyl)-3-(4-fluorophenyl)thiourea::1-[2,5-bis(chloranyl)phenyl]-3-(4-fluorophenyl)thiourea::MLS000672056::N-(2,5-dichlorophenyl)-N'-(4-fluorophenyl)thiourea::SMR000293493::cid_976468

SMILES Cc1cccc(-c2nc3n(c2-c2ccc(F)c(NC(=O)CCN(C)C)c2)CCN3)n1

InChI Key InChIKey=VSXSGRCNEZXNPV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72437   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 72437BDBM72437(3-(Dimethylamino)-N-(2-fluoro-5-(6- (6-methylpyrid...)
Affinity DataIC50: 1nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent