BDBM724516 US20250066363, Example 48

SMILES Cc1nc2c(N3C[C@@H](C)N([C@@H](c4ccc5cc(F)ccc5n4)C(C)C)C[C@@H]3C)nc(=O)n(C)c2n1C[C@@H]1CCCO1

InChI Key InChIKey=TVPLSLPCQVKENH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724516   

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM724516(US20250066363, Example 48)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM724516(US20250066363, Example 48)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent