BDBM724523 6-((2S,5R)-4-((R)-1-(4-(difluoromethyl)-3-fluorophenyl)-2-methylpropyl)-2,5-dimethylpiperazin-1-yl)-3,8-dimethyl-9-(((S)-tetrahydrofuran-2-yl)methyl)-3,9-dihydro-2H-purin-2-one::US20250066363, Example 55

SMILES Cc1nc2c(N3C[C@@H](C)N([C@H](c4ccc(C(F)F)c(F)c4)C(C)C)C[C@@H]3C)nc(=O)n(C)c2n1C[C@@H]1CCCO1

InChI Key InChIKey=BECLEGXRCYFHQK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724523   

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM724523(6-((2S,5R)-4-((R)-1-(4-(difluoromethyl)-3-fluoroph...)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM724523(6-((2S,5R)-4-((R)-1-(4-(difluoromethyl)-3-fluoroph...)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent