BDBM724537 6-((2S,5R)-5-ethyl-2-methyl-4-((R)-1-(4-(trifluoromethyl)phenyl)propyl)piperazin-1-yl)-9-(((2R,3S)-3-hydroxytetrahydrofuran-2-yl)methyl)-3,8-dimethyl-3,9-dihydro-2H-purin-2-one::US20250066363, Example 69

SMILES CC[C@@H]1CN(c2nc(=O)n(C)c3c2nc(C)n3C[C@H]2OCC[C@@H]2O)[C@@H](C)CN1[C@@H](CC)c1ccc(C(F)(F)F)cc1

InChI Key InChIKey=OIEJPLZLZOQVFE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724537   

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM724537(6-((2S,5R)-5-ethyl-2-methyl-4-((R)-1-(4-(trifluoro...)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM724537(6-((2S,5R)-5-ethyl-2-methyl-4-((R)-1-(4-(trifluoro...)
Affinity DataIC50: 10nMAssay Description:For compound inhibition studies, 40 nL test compound in DMSO was added to wells of white polystyrene plates in 384-well (Greiner, #784075) or 1536-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent