BDBM724976 US12240835, Example 2

SMILES O=C(Nc1ccc(OC(F)(F)Cl)cc1)c3cc(c2cncnc2)c4c(c3)ncn4[C@@H]5C[C@H](O)C5

InChI Key InChIKey=DRLGQKRSNKZMSD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724976   

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM724976(US12240835, Example 2)
Affinity DataIC50: 0.370nMAssay Description:ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/6/2025
Entry Details
US Patent