BDBM72594 (E)-3-[5-chloro-1-(1,1-diketothiolan-3-yl)-3-methyl-pyrazol-4-yl]acrylic acid [2-(4-ethylanilino)-2-keto-ethyl] ester::(E)-3-[5-chloro-1-(1,1-dioxo-3-thiolanyl)-3-methyl-4-pyrazolyl]-2-propenoic acid [2-(4-ethylanilino)-2-oxoethyl] ester::MLS001033154::SMR000363612::[2-(4-ethylanilino)-2-oxoethyl] (E)-3-[5-chloro-1-(1,1-dioxothiolan-3-yl)-3-methylpyrazol-4-yl]prop-2-enoate::[2-[(4-ethylphenyl)amino]-2-oxidanylidene-ethyl] (E)-3-[1-[1,1-bis(oxidanylidene)thiolan-3-yl]-5-chloranyl-3-methyl-pyrazol-4-yl]prop-2-enoate::cid_5863039

SMILES COc1ncnc(C2CC2)c1-c1ncc2c3ccncc3n(Cc3ccc(-c4nc(C(F)(F)F)c(C)n4C)cc3)c2n1

InChI Key InChIKey=NQFQGUVOQICEMN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72594   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandChemical structure of BindingDB Monomer ID 72594BDBM72594(US20250368667, Compound 151)
Affinity DataIC50: 1nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent