BDBM726355 2-[5,6-difluoro-2-[[6-methoxy-5-(4-methylpiperazine-1-carbonyl)-1,3-benzothiazol-2-yl]methylcarbamoyl]indan-2-yl]acetic Acid::US12247013, Example 34

SMILES COc1cc2sc(CNC(=O)C3(CC(=O)O)Cc4cc(F)c(F)cc4C3)nc2cc1C(=O)N1CCN(C)CC1

InChI Key InChIKey=XFQZRLAWDAIPDT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 726355   

TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Antabio

US Patent
LigandPNGBDBM726355(2-[5,6-difluoro-2-[[6-methoxy-5-(4-methylpiperazin...)
Affinity DataKi: <50nMAssay Description:Method: 10 to 140 ng/ml purified LasB is incubated with 250 μM Abz-Ala-Gly-Leu-Ala-p-Nitro-Benzyl-Amide in 50 mM Tris-HCl pH 7.4, 2.5 mM CaCl2), 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent