BDBM726419 2-(2-(3-cyano-4-oxo- 1-((S)-1-(6- (trifluoromethyl) pyridin-3-yl)ethyl)- 4,5-dihydro-1H- pyrazolo[3,4- d]pyrimidin-6- yl)cyclobutyl) pyridine 1-oxide::US12247031, Example 10

SMILES C[C@@H](c1ccc(C(F)(F)F)nc1)n1nc(C#N)c2c(=O)[nH]c(C3CCC3c3nccc[n+]3[O-])nc21

InChI Key InChIKey=OYGDHXMJURBDNA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 726419   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM726419(2-(2-(3-cyano-4-oxo- 1-((S)-1-(6- (trifluoromethyl...)
Affinity DataKi:  249nMAssay Description:Assays were performed at room temperature in 384-well microtiter plates with an incubation volume of 20.2 μL. Solutions of test compounds were prepar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/15/2025
Entry Details
US Patent