BDBM728040 (Z)-1-acetyl-2- ((6-((4-(oxetan- 3-yl)piperazin-1- yl)methyl)quinolin- 2-yl)methylene)- indolin-3-one::US20250091994, Example 74
SMILES CC(=O)n6c(=Cc4ccc3cc(CN2CCN(C1COC1)CC2)ccc3n4)c(=O)c5ccccc56
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728040
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 710nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
