BDBM728059 1-acetyl-2-((6- (morpholine-4- carbonyl)-4-(2- phenylpyridin-3- yl)quinolin-2-yl)- methylene)indolin- 3-one::US20250091994, Example 94
SMILES CC(=O)N1C(=Cc2cc(-c3cccnc3-c3ccccc3)c3cc(C(=O)N4CCOCC4)ccc3n2)C(=O)c2ccccc21
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728059
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 660nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
