BDBM728060 (Z)-2-((4-([1,1''- biphenyl]-2-yl)-6- (4-(oxetan-3-yl)- piperazine-1- carbonyl)quinolin- 2-yl)methylene)- 1-acetylindolin-3- one::US20250091994, Example 95
SMILES CC(=O)n8c(=Cc6cc(c1ccccc1c2ccccc2)c5cc(C(=O)N4CCN(C3COC3)CC4)ccc5n6)c(=O)c7ccccc78
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728060
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 440nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
